NeoFertility is a restorative reproductive medicine clinical framework developed in Dublin, Ireland, that integrates cycle charting, targeted hormonal investigation, and surgical correction to identify and treat the root causes of infertility, recurrent pregnancy loss, and at-risk pregnancy.1 The approach builds on the diagnostic foundation of NaProTechnology while expanding the evaluation panel to include reproductive immunology, androgen profiling, and in-depth assessment of both partners.
NeoFertility structures its work in three sequential phases. Phase 1 is diagnostic: a thorough workup of cycle patterns, hormonal function, anatomy, and immune markers for both partners. Phase 2 is treatment and cycle optimization: addressing the conditions identified, which may include surgical intervention, hormonal support, nutritional correction, or immunological management. Phase 3 focuses on conception timing, confirmed ovulation, and follow-through support from the peri-conception period.2
NeoFertility is method-agnostic with respect to fertility charting: it accepts data from any FABM, not only the Creighton Model, and integrates ChartNeo as its digital charting platform. Its expanded hormonal panel includes evaluation for conditions such as diminished ovarian reserve, where DHEA supplementation may be considered alongside other restorative interventions based on the individual evaluation. Immune-related contributors to implantation failure and recurrent loss are assessed within the immune-modifying framework.
The framework is restorative in principle: the clinical question begins with why conception has not occurred or why pregnancies have not continued. Treatment targets those underlying causes rather than bypassing them. A 2025 retrospective cohort study examining restorative reproductive medicine outcomes reported clinically significant live birth rates in couples who had previously failed to conceive, supporting the model of root-cause diagnosis before any procedural intervention.2
Cited in this entry
- NeoFertility. https://neofertility.ie/
- Boyle P, Toth A, Minjeur M, Turczynski C. Restorative reproductive medicine (RRM) outcomes compared to in-vitro fertilization (IVF) for the treatment of infertility: a retrospective evaluation of a 2019 clinic cohort. https://rrmacademy.org/library/restorative-reproductive-medicine-rrm-outcomes-compared-to-in-vitro-fertilization-rec4qqhafqb8stlnd/
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