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    <title>RRM Academy Research Library</title>
    <link>https://rrmacademy.org/library/</link>
    <description>The latest additions to the RRM Academy Research Library: curated research on restorative reproductive medicine, NaProTechnology, fertility awareness-based methods, endometriosis, PCOS, and reproductive surgery.</description>
    <language>en-us</language>
    <lastBuildDate>Sun, 24 May 2026 01:33:42 GMT</lastBuildDate>
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    <item>
      <title><![CDATA[Long-term follow-up of ICSI-conceived offspring compared with spontaneously conceived offspring: a systematic review of health outcomes beyond the neonatal period]]></title>
      <link>https://rrmacademy.org/library/longterm-followup-of-icsiconceived-offspring-compared-with-spontaneously-conceiv-gx0otcdx/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/longterm-followup-of-icsiconceived-offspring-compared-with-spontaneously-conceiv-gx0otcdx/</guid>
      <description><![CDATA[Catford SR, McLachlan RI, O'Bryan MK, Halliday JL -- Andrology (2018)

BACKGROUND: A significant increase in the use of intracytoplasmic sperm injection (ICSI) since its introduction in 1992 has been observed worldwide, including beyond its original intended use for severe male factor infertility. Concerns regarding ICSI include the effects of poor quality spermatozoa on offspring health and future fertility, and of the technique itself. The health and development of ICSI-conceived children beyond early infancy have not been comprehensively assessed. OBJECTIVE: A…]]></description>
      <pubDate>Sun, 24 May 2026 01:33:42 GMT</pubDate>
      <dc:creator><![CDATA[Catford SR, McLachlan RI, O'Bryan MK, Halliday JL]]></dc:creator>
      <category>Andrology/Male Factor</category>
    </item>
    <item>
      <title><![CDATA[Are we overusing IVF?]]></title>
      <link>https://rrmacademy.org/library/are-we-overusing-ivf-kygs3hhr/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/are-we-overusing-ivf-kygs3hhr/</guid>
      <description><![CDATA[Kamphuis EI, Bhattacharya S, van der Veen F, Mol BW, Templeton A -- BMJ (2014)

The indications for IVF have expanded from tubal disorders to many causes of subfertility, including unexplained. But with limited evidence underpinning its extended remit Esme Kamphuis and colleagues explain how the risks could outweigh the benefits.]]></description>
      <pubDate>Sun, 24 May 2026 01:33:25 GMT</pubDate>
      <dc:creator><![CDATA[Kamphuis EI, Bhattacharya S, van der Veen F, Mol BW, Templeton A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Emotional distress in infertile women and failure of assisted reproductive technologies: meta-analysis of prospective psychosocial studies]]></title>
      <link>https://rrmacademy.org/library/emotional-distress-in-infertile-women-and-failure-of-assisted-reproductive-techn-bxemybzi/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/emotional-distress-in-infertile-women-and-failure-of-assisted-reproductive-techn-bxemybzi/</guid>
      <description><![CDATA[Boivin J, Griffiths E, Venetis CA -- BMJ (2011)

OBJECTIVE: To examine whether pretreatment emotional distress in women is associated with achievement of pregnancy after a cycle of assisted reproductive technology. DESIGN: Meta-analysis of prospective psychosocial studies. DATA SOURCES: PubMed, Medline, Embase, PsycINFO, PsychNET, ISI Web of Knowledge, and ISI Web of Science were searched for articles published from 1985 to March 2010 (inclusive). We also undertook a hand search of reference lists and contacted 29 authors. Eligible studies…]]></description>
      <pubDate>Fri, 22 May 2026 18:06:12 GMT</pubDate>
      <dc:creator><![CDATA[Boivin J, Griffiths E, Venetis CA]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The effectiveness and safety of restorative reproductive medicine (RRM) compared to assisted reproductive technology or medically unassisted conception: a systematic review]]></title>
      <link>https://rrmacademy.org/library/the-effectiveness-and-safety-of-restorative-reproductive-medicine-rrm-compared-t-vrqg1wuo/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-effectiveness-and-safety-of-restorative-reproductive-medicine-rrm-compared-t-vrqg1wuo/</guid>
      <description><![CDATA[Ganci D, Steeper M, Polyakov A, Sunkara SK, Wilkinson J, Lensen S -- Fertility and Sterility (2026)

IMPORTANCE: Restorative Reproductive Medicine (RRM) aims to restore fertility by diagnosing and treating the underlying causes of infertility. RRM is frequently promoted as an alternative to assisted reproductive technology (ART), despite uncertainty regarding its comparative effectiveness and safety. Where delayed childbearing and infertility are becoming more common, reliance on optimization of natural physiology alone may delay effective treatment and compromise reproductive outcomes. A…]]></description>
      <pubDate>Fri, 22 May 2026 04:28:33 GMT</pubDate>
      <dc:creator><![CDATA[Ganci D, Steeper M, Polyakov A, Sunkara SK, Wilkinson J, Lensen S]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study]]></title>
      <link>https://rrmacademy.org/library/role-of-maternal-age-and-pregnancy-history-in-risk-of-miscarriage-prospective-re-4ry4pl6s/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/role-of-maternal-age-and-pregnancy-history-in-risk-of-miscarriage-prospective-re-4ry4pl6s/</guid>
      <description><![CDATA[Magnus MC, Wilcox AJ, Morken NH, Weinberg CR, Haberg SE -- BMJ (2019)

OBJECTIVES: To estimate the burden of miscarriage in the Norwegian population and to evaluate the associations with maternal age and pregnancy history. DESIGN: Prospective register based study. SETTING: Medical Birth Register of Norway, the Norwegian Patient Register, and the induced abortion register. PARTICIPANTS: All Norwegian women that were pregnant between 2009-13. MAIN OUTCOME MEASURE: Risk of miscarriage according to the woman's age and pregnancy history estimated by logistic…]]></description>
      <pubDate>Thu, 14 May 2026 13:25:30 GMT</pubDate>
      <dc:creator><![CDATA[Magnus MC, Wilcox AJ, Morken NH, Weinberg CR, Haberg SE]]></dc:creator>
      <category>Pregnancy</category>
    </item>
    <item>
      <title><![CDATA[Recurrent pregnancy loss: a committee opinion]]></title>
      <link>https://rrmacademy.org/library/recurrent-pregnancy-loss-a-committee-opinion-ekx8pstx/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/recurrent-pregnancy-loss-a-committee-opinion-ekx8pstx/</guid>
      <description><![CDATA[Practice Committee of the American Society for Reproductive Medicine -- Fertility and Sterility (2026)

Current strategies for the assessment and treatment of recurrent pregnancy loss are discussed. This replaces the previous document, titled, "Evaluation and treatment of recurrent pregnancy loss: a committee opinion," last published in 2012.]]></description>
      <pubDate>Thu, 14 May 2026 13:25:29 GMT</pubDate>
      <dc:creator><![CDATA[Practice Committee of the American Society for Reproductive Medicine]]></dc:creator>
      <category>Pregnancy</category>
    </item>
    <item>
      <title><![CDATA[Evidence-based guideline: unexplained infertility]]></title>
      <link>https://rrmacademy.org/library/evidencebased-guideline-unexplained-infertility-xyenlqkh/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/evidencebased-guideline-unexplained-infertility-xyenlqkh/</guid>
      <description><![CDATA[Romualdi D, Ata B, Bhattacharya S, Bosch E, Costello M, Gersak K, Homburg R, Mincheva M, Norman RJ, Piltonen T, Dos Santos-Ribeiro S, Scicluna D, Somers S, Sunkara SK, Verhoeve HR, Le Clef N -- Hum Reprod (2023)

Guideline Group on Unexplained Infertility; Romualdi D(1), Ata B(2)(3),  Bhattacharya S(4), Bosch E(5), Costello M(6)(7), Gersak K(8), Homburg R(9),  Mincheva M(10), Norman RJ(7)(11), Piltonen T(12), Dos Santos-Ribeiro S(13),  Scicluna D(14), Somers S(15), Sunkara SK(16), Verhoeve HR(17), Le Clef N(18).]]></description>
      <pubDate>Tue, 12 May 2026 04:11:02 GMT</pubDate>
      <dc:creator><![CDATA[Romualdi D, Ata B, Bhattacharya S, Bosch E, Costello M, Gersak K, Homburg R, Mincheva M, Norman RJ, Piltonen T, Dos Santos-Ribeiro S, Scicluna D, Somers S, Sunkara SK, Verhoeve HR, Le Clef N]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The longer-term effects of IVF on offspring from childhood to adolescence]]></title>
      <link>https://rrmacademy.org/library/the-longerterm-effects-of-ivf-on-offspring-from-childhood-to-adolescence-86gdjdzj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-longerterm-effects-of-ivf-on-offspring-from-childhood-to-adolescence-86gdjdzj/</guid>
      <description><![CDATA[Hart RJ, Wijs LA -- Front Reprod Health (2022)

It is well established that there are increased pregnancy-related complications  for a woman who conceives through assisted reproductive treatment (ART).  Furthermore, it is known that the risk to the child born is greater, believed to  be related to prematurity and growth restriction. Studies have also reported  epigenetic changes in the DNA of offspring conceived through ART. In addition,  it is believed that they have a greater risk of congenital malformations,  although some of these risks…]]></description>
      <pubDate>Tue, 12 May 2026 04:11:01 GMT</pubDate>
      <dc:creator><![CDATA[Hart RJ, Wijs LA]]></dc:creator>
      <category>General OB/GYN</category>
    </item>
    <item>
      <title><![CDATA[Worldwide decline of IVF birth rates and its probable causes]]></title>
      <link>https://rrmacademy.org/library/worldwide-decline-of-ivf-birth-rates-and-its-probable-causes-kyaowcwt/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/worldwide-decline-of-ivf-birth-rates-and-its-probable-causes-kyaowcwt/</guid>
      <description><![CDATA[Gleicher N, Kushnir VA, Barad DH -- Hum Reprod Open (2019)

With steadily improving pregnancy and live birth rates, IVF over approximately  the first two and a half decades evolved into a highly successful treatment for  female and male infertility, reaching peak live birth rates by 2001-2002.  Plateauing rates, thereafter, actually started declining in most regions of the  world. We here report worldwide IVF live birth rates between 2004 and 2016,  defined as live births per fresh IVF/ICSI cycle started, and how the  introduction of certain practice…]]></description>
      <pubDate>Tue, 12 May 2026 04:11:01 GMT</pubDate>
      <dc:creator><![CDATA[Gleicher N, Kushnir VA, Barad DH]]></dc:creator>
      <category>Research Methodology</category>
    </item>
    <item>
      <title><![CDATA[Observational retrospective study of US national utilisation patterns and live birth rates for various ovarian stimulation protocols for in vitro fertilisation]]></title>
      <link>https://rrmacademy.org/library/observational-retrospective-study-of-us-national-utilisation-patterns-and-live-b-su4zwz68/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/observational-retrospective-study-of-us-national-utilisation-patterns-and-live-b-su4zwz68/</guid>
      <description><![CDATA[Kushnir VA, Darmon SK, Barad DH, Gleicher N -- BMJ Open (2018)

OBJECTIVE: Alternative ovarian stimulation protocols for in vitro fertilisation  (IVF) have grown in popularity. Yet, patient populations best suited for these  protocols have not been defined. Our objective was, therefore, to determine  national IVF utilisation patterns and live birth rates of various ovarian  stimulation protocols. DESIGN: Retrospective cohort study. SETTING: Academic-affiliated private fertility centre. PARTICIPANTS: Aggregate data published by Society for Assisted…]]></description>
      <pubDate>Tue, 12 May 2026 04:11:01 GMT</pubDate>
      <dc:creator><![CDATA[Kushnir VA, Darmon SK, Barad DH, Gleicher N]]></dc:creator>
      <category>Research Methodology</category>
    </item>
    <item>
      <title><![CDATA[Direct-to-consumer advertising of success rates for medically assisted reproduction: a review of national clinic websites]]></title>
      <link>https://rrmacademy.org/library/directtoconsumer-advertising-of-success-rates-for-medically-assisted-reproductio-p8drpr60/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/directtoconsumer-advertising-of-success-rates-for-medically-assisted-reproductio-p8drpr60/</guid>
      <description><![CDATA[Wilkinson J, Vail A, Roberts SA -- BMJ Open (2017)

OBJECTIVES: To establish how medically assisted reproduction (MAR) clinics  report success rates on their websites. SETTING: Websites of private and NHS clinics offering in vitro fertilisation  (IVF) in the UK. PARTICIPANTS: We identified clinics offering IVF using the Choose a Fertility  Clinic facility on the website of the Human Fertilisation and Embryology  Authority (HFEA). Of 81 clinics identified, a website could not be found for 2,  leaving 79 for inclusion in the analysis. PRIMARY AND…]]></description>
      <pubDate>Tue, 12 May 2026 04:11:01 GMT</pubDate>
      <dc:creator><![CDATA[Wilkinson J, Vail A, Roberts SA]]></dc:creator>
      <category>Research Methodology</category>
    </item>
    <item>
      <title><![CDATA[Practical Clinical and Diagnostic Pathway for the Investigation of the Infertile Couple]]></title>
      <link>https://rrmacademy.org/library/practical-clinical-and-diagnostic-pathway-for-the-investigation-of-the-infertile-hahaknth/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/practical-clinical-and-diagnostic-pathway-for-the-investigation-of-the-infertile-hahaknth/</guid>
      <description><![CDATA[Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, Ferlin A, Lanzone A, Tomei F, Engl B, Rienzi L, De Santis L, Coticchio G, Smith L, Cannarella R, Anastasi A, Menegazzo M, Stuppia L, Corsini C, Foresta C -- Front Endocrinol (Lausanne) (2020)

CAPSULE: This expert opinion summarizes current knowledge on risk factors for infertility and identifies a practical clinical and diagnostic approach for the male and female partners of an infertile couple aimed to improve the investigation and management of fertility problems. BACKGROUND: Infertility represents an important and growing health problem affecting up to 16% of couples worldwide. In most cases, male, female, or combined factor can be identified, and different causes or risk factors…]]></description>
      <pubDate>Mon, 11 May 2026 23:38:53 GMT</pubDate>
      <dc:creator><![CDATA[Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, Ferlin A, Lanzone A, Tomei F, Engl B, Rienzi L, De Santis L, Coticchio G, Smith L, Cannarella R, Anastasi A, Menegazzo M, Stuppia L, Corsini C, Foresta C]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The impact of consumer affordability on access to assisted reproductive technologies and embryo transfer practices: an international analysis]]></title>
      <link>https://rrmacademy.org/library/the-impact-of-consumer-affordability-on-access-to-assisted-reproductive-technolo-p4vbfxve/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-impact-of-consumer-affordability-on-access-to-assisted-reproductive-technolo-p4vbfxve/</guid>
      <description><![CDATA[Chambers GM, Hoang VP, Sullivan EA, Chapman MG, Ishihara O, Zegers-Hochschild F, Nygren KG, Adamson GD -- Fertil Steril (2014)

Comment in Fertil Steril. 2014 Jan;101(1):47-8. doi: 10.1016/j.fertnstert.2013.09.043.
 OBJECTIVE: To systematically quantify the impact of consumer cost on assisted reproduction technology (ART) utilization and numbers of embryos transferred. DESIGN: Ordinary least squared (OLS) regression models were constructed to measure the independent impact of ART affordability-measured as consumer cost relative to average disposable income-on ART utilization and embryo transfer practices. SETTING: Not…]]></description>
      <pubDate>Mon, 11 May 2026 23:38:53 GMT</pubDate>
      <dc:creator><![CDATA[Chambers GM, Hoang VP, Sullivan EA, Chapman MG, Ishihara O, Zegers-Hochschild F, Nygren KG, Adamson GD]]></dc:creator>
      <category>Economics</category>
    </item>
    <item>
      <title><![CDATA[Live-Birth Rate Associated With Repeat In Vitro Fertilization Treatment Cycles]]></title>
      <link>https://rrmacademy.org/library/livebirth-rate-associated-with-repeat-in-vitro-fertilization-treatment-cycles-rpeh9knj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/livebirth-rate-associated-with-repeat-in-vitro-fertilization-treatment-cycles-rpeh9knj/</guid>
      <description><![CDATA[Smith ADAC, Tilling K, Nelson SM, Lawlor DA -- JAMA (2015)

Comment in BMJ. 2015 Dec 23;351:h6913. doi: 10.1136/bmj.h6913. JAMA. 2015 Dec 22-29;314(24):2627-9. doi: 10.1001/jama.2015.17297.
 IMPORTANCE: The likelihood of achieving a live birth with repeat in vitro fertilization (IVF) is unclear, yet treatment is commonly limited to 3 or 4 embryo transfers. OBJECTIVE: To determine the live-birth rate per initiated ovarian stimulation IVF cycle and with repeated cycles. DESIGN, SETTING, AND PARTICIPANTS: Prospective study of 156,947 UK women who received…]]></description>
      <pubDate>Mon, 11 May 2026 23:38:52 GMT</pubDate>
      <dc:creator><![CDATA[Smith ADAC, Tilling K, Nelson SM, Lawlor DA]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Point of failure as a predictor of in vitro fertilization treatment discontinuation]]></title>
      <link>https://rrmacademy.org/library/point-of-failure-as-a-predictor-of-in-vitro-fertilization-treatment-discontinuat-uq5l5dgq/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/point-of-failure-as-a-predictor-of-in-vitro-fertilization-treatment-discontinuat-uq5l5dgq/</guid>
      <description><![CDATA[Pearson KR, Hauser R, Cramer DW, Missmer SA -- Fertil Steril (2009)

Among 2,245 women, those who experienced a chemical pregnancy that failed to progress to a clinically recognized pregnancy or a spontaneous abortion on their first IVF cycle were more likely to discontinue IVF treatment than those whose first cycle ended before embryo transfer or who did not have a positive pregnancy test after transfer. However, among women who did continue to a second IVF cycle, those who had at least a chemical pregnancy on the first cycle were more likely to have a live…]]></description>
      <pubDate>Mon, 11 May 2026 23:38:52 GMT</pubDate>
      <dc:creator><![CDATA[Pearson KR, Hauser R, Cramer DW, Missmer SA]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Cumulative live-birth rates after in vitro fertilization]]></title>
      <link>https://rrmacademy.org/library/cumulative-livebirth-rates-after-in-vitro-fertilization-c1konion/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/cumulative-livebirth-rates-after-in-vitro-fertilization-c1konion/</guid>
      <description><![CDATA[Malizia BA, Hacker MR, Penzias AS -- N Engl J Med (2009)

BACKGROUND: Outcomes of in vitro fertilization (IVF) treatment are traditionally reported as pregnancies per IVF cycle. However, a couple's primary concern is the chance of a live birth over an entire treatment course. METHODS: We estimated cumulative live-birth rates among patients undergoing their first fresh-embryo, nondonor IVF cycle between 2000 and 2005 at one large center. Couples were followed until either discontinuation of treatment or delivery of a live-born infant. Analyses were…]]></description>
      <pubDate>Mon, 11 May 2026 23:38:52 GMT</pubDate>
      <dc:creator><![CDATA[Malizia BA, Hacker MR, Penzias AS]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Exercise-associated menstrual disturbances]]></title>
      <link>https://rrmacademy.org/library/exercise-associated-menstrual-disturbances-zkn3bzbz/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/exercise-associated-menstrual-disturbances-zkn3bzbz/</guid>
      <description><![CDATA[Prior JC -- Reproductive Endocrinology, Surgery and Technology (1996)]]></description>
      <pubDate>Tue, 05 May 2026 17:09:51 GMT</pubDate>
      <dc:creator><![CDATA[Prior JC]]></dc:creator>
      <category>Menstrual Cycle</category>
    </item>
    <item>
      <title><![CDATA[Influence of race and ethnicity on in vitro fertilization outcomes: systematic review]]></title>
      <link>https://rrmacademy.org/library/influence-of-race-and-ethnicity-on-in-vitro-fertilization-outcomes-systematic-re-wipmfhhw/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/influence-of-race-and-ethnicity-on-in-vitro-fertilization-outcomes-systematic-re-wipmfhhw/</guid>
      <description><![CDATA[Humphries LA, Chang O, Humm K, Sakkas D, Hacker MR -- American Journal of Obstetrics and Gynecology (2016)

Objective: We conducted a systematic review to evaluate the influence of race and ethnicity on clinical pregnancy and live birth outcomes after in vitro fertilization (IVF).StudyWe searched PubMed, EMBASE, Web of Science, CINAHL, POPLINE, and Cochrane Central, and hand-searched relevant articles published through July 22, 2015.Study appraisal and synthesis methodsTwo reviewers independently evaluated abstracts to identify studies that compared clinical pregnancy rates and live birth rates for…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:15 GMT</pubDate>
      <dc:creator><![CDATA[Humphries LA, Chang O, Humm K, Sakkas D, Hacker MR]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[[Occupational, educational and residential factors are associated with the outcomes of in vitro fertilization-embryo transfer]]]></title>
      <link>https://rrmacademy.org/library/occupational-educational-and-residential-factors-are-associated-with-the-outcome-br4qvdxj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/occupational-educational-and-residential-factors-are-associated-with-the-outcome-br4qvdxj/</guid>
      <description><![CDATA[Hua R, Song Y, Wu B, Ni H, Yang X, Guo Y, Li H, Quan S, Yu Y -- Nan fang yi ke da xue xue bao = Journal of Southern Medical University (2016)

OBJECTIVE: To investigate the associations of occupational, educational and residential factors with the outcomes of in vitro fertilization -embryo transfer (IVF-ET).

METHODS: A retrospective analysis was conducted among 3998 patients undergoing the first treatment with IVF-ET and 3064 perinatal infants in our center between January, 2010 and June, 2014. The relation of the patients' occupation, educational background, and residence registry with IVF-ET outcomes was analyzed.

RESULTS: The…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:15 GMT</pubDate>
      <dc:creator><![CDATA[Hua R, Song Y, Wu B, Ni H, Yang X, Guo Y, Li H, Quan S, Yu Y]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Epigenetic imprinting during assisted reproductive technologies: The effect of temporal and cumulative fluctuations in methionine cycling on the DNA methylation state]]></title>
      <link>https://rrmacademy.org/library/epigenetic-imprinting-during-assisted-reproductive-technologies-the-effect-of-te-frnzgdq8/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/epigenetic-imprinting-during-assisted-reproductive-technologies-the-effect-of-te-frnzgdq8/</guid>
      <description><![CDATA[Hoeijmakers L, Kempe H, Verschure PJ -- Molecular Reproduction and Development (2016)

SUMMARYAssisted reproductive technology (ART) exposes gametes and embryos to an artificial environment that does not resemble the conditions of natural conception, and therefore might change epigenetic regulation of genes that are imprinted during development. In the present review, we discuss the relationship between susceptibility of specific genes to receive an altered epigenetic composition during ART processes, possibly via alterations in the biochemical folate and methionine cycle. We…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:14 GMT</pubDate>
      <dc:creator><![CDATA[Hoeijmakers L, Kempe H, Verschure PJ]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Birth Defects in Singleton versus Multiple ART Births in Japan (2004–2008)]]></title>
      <link>https://rrmacademy.org/library/birth-defects-in-singleton-versus-multiple-art-births-in-japan-20042008-aulyt5gj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/birth-defects-in-singleton-versus-multiple-art-births-in-japan-20042008-aulyt5gj/</guid>
      <description><![CDATA[Ooki S -- Journal of Pregnancy (2011)

Despite the widespread use of operative cholangiography and choledoschoscopy, stones are still left behind after exploration of the common bile duct. Reoperation is associated with a significant morbidity and mortality. The use of a steerable catheter-basket technique has enabled stones to be removed from the biliary tract in the vast majority of cases without significant complications and has practically eliminated the need for further surgery.]]></description>
      <pubDate>Sat, 02 May 2026 05:25:13 GMT</pubDate>
      <dc:creator><![CDATA[Ooki S]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Perinatal outcomes among children born by assisted reproductive techniques—a hospital-based case control study]]></title>
      <link>https://rrmacademy.org/library/perinatal-outcomes-among-children-born-by-assisted-reproductive-techniquesa-hosp-kdnfnlyi/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/perinatal-outcomes-among-children-born-by-assisted-reproductive-techniquesa-hosp-kdnfnlyi/</guid>
      <description><![CDATA[Gupta P, Nayan N, Sharma M -- Medical Journal Armed Forces India (2012)]]></description>
      <pubDate>Sat, 02 May 2026 05:25:12 GMT</pubDate>
      <dc:creator><![CDATA[Gupta P, Nayan N, Sharma M]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Adverse Perinatal Events Associated with ART]]></title>
      <link>https://rrmacademy.org/library/adverse-perinatal-events-associated-with-art-roq25jdi/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/adverse-perinatal-events-associated-with-art-roq25jdi/</guid>
      <description><![CDATA[Skora D, Frankfurter D -- Seminars in Reproductive Medicine (2012)

Since the advent of ART, much research has focused on the potential adverse for resultant harm. Prematurity, low birth-weight, PIH, congenital malformations, and CP are closely tied to multiple gestation. With the increase in elective single embryo transfer, there will be a reduction in adversity related to multiple birth. It is understood that underlying causes of infertility, including advanced maternal age, PCOS, thyroid disease, and uterine fibroids, predispose to adverse outcomes. However,…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:11 GMT</pubDate>
      <dc:creator><![CDATA[Skora D, Frankfurter D]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[[The prognosis for children born after assisted reproduction]]]></title>
      <link>https://rrmacademy.org/library/the-prognosis-for-children-born-after-assisted-reproduction-t0pu2vyw/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-prognosis-for-children-born-after-assisted-reproduction-t0pu2vyw/</guid>
      <description><![CDATA[Henningsen AK, Loft A, Malchau SS, Pinborg A -- Ugeskrift for laeger (2012)

Children who are born after assisted reproduction (ART) have a slightly increased risk of being born preterm, of having low birthweight and a higher perinatal mortality than spontaneously conceived children. The higher rate of multiple births among women having had ART can to some extent explain this. However, adverse outcomes persist even in ART singletons. The characteristics of the infertile parents have negative effects on the outcome, but also the hormone stimulation and the in vitro…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:10 GMT</pubDate>
      <dc:creator><![CDATA[Henningsen AK, Loft A, Malchau SS, Pinborg A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Characterization of DNA methylation errors in patients with imprinting disorders conceived by assisted reproduction technologies]]></title>
      <link>https://rrmacademy.org/library/characterization-of-dna-methylation-errors-in-patients-with-imprinting-disorders-n3rtt3il/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/characterization-of-dna-methylation-errors-in-patients-with-imprinting-disorders-n3rtt3il/</guid>
      <description><![CDATA[Hiura H, Okae H, Miyauchi N, Sato F, Sato A, Van De Pette M, John RM, Kagami M, Nakai K, Soejima H, Ogata T, Arima T -- Human Reproduction (2012)

Background: There is an increased incidence of rare imprinting disorders associated with assisted reproduction technologies (ARTs). The identification of epigenetic changes at imprinted loci in ART infants has led to the suggestion that the techniques themselves may predispose embryos to acquire imprinting errors and diseases. However, it is still unknown at what point(s) these imprinting errors arise, or the risk factors.

Methods: In 2009 we conducted a Japanese nationwide epidemiological…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:10 GMT</pubDate>
      <dc:creator><![CDATA[Hiura H, Okae H, Miyauchi N, Sato F, Sato A, Van De Pette M, John RM, Kagami M, Nakai K, Soejima H, Ogata T, Arima T]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The risk for four specific congenital heart defects associated with assisted reproductive techniques: a population-based evaluation]]></title>
      <link>https://rrmacademy.org/library/the-risk-for-four-specific-congenital-heart-defects-associated-with-assisted-rep-hqhbc8dj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-risk-for-four-specific-congenital-heart-defects-associated-with-assisted-rep-hqhbc8dj/</guid>
      <description><![CDATA[Tararbit K, Lelong N, Thieulin AC, Houyel L, Bonnet D, Goffinet F, Khoshnood B,  -- Human Reproduction (2012)

Study question: Are the risks of hypoplastic left heart syndrome, transposition of great arteries, tetralogy of Fallot (TOF) and coarctation of the aorta increased in infants conceived by different assisted reproductive techniques (ARTs)?Study answerARTs, and particularly intracytoplasmic sperm injection (ICSI), are specifically associated with a higher risk of TOF.What is already knownARTs are associated with an increase in the overall risk of birth defects. The risk for congenital heart…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:09 GMT</pubDate>
      <dc:creator><![CDATA[Tararbit K, Lelong N, Thieulin AC, Houyel L, Bonnet D, Goffinet F, Khoshnood B, ]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Congenital anomalies after assisted reproductive technology]]></title>
      <link>https://rrmacademy.org/library/congenital-anomalies-after-assisted-reproductive-technology-29ddwypd/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/congenital-anomalies-after-assisted-reproductive-technology-29ddwypd/</guid>
      <description><![CDATA[Pinborg A, Henningsen AKA, Malchau SS, Loft A -- Fertility and Sterility (2013)

Worldwide, more than 5 million children have been born after assisted reproductive technology (ART), and in many developed countries ART infants represent more than 1% of the birth cohorts. It is well known that ART children are at increased risk of congenital malformations even after adjustment for known confounders such as maternal age. The proportion of ART children is not negligible, and knowledge about the causes of the higher risk of congenital malformations is crucial to develop…]]></description>
      <pubDate>Sat, 02 May 2026 05:25:02 GMT</pubDate>
      <dc:creator><![CDATA[Pinborg A, Henningsen AKA, Malchau SS, Loft A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Analysis of birth defects among children 3 years after conception through assisted reproductive technology in China]]></title>
      <link>https://rrmacademy.org/library/analysis-of-birth-defects-among-children-3-years-after-conception-through-assist-g92bbx2o/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/analysis-of-birth-defects-among-children-3-years-after-conception-through-assist-g92bbx2o/</guid>
      <description><![CDATA[Yin L, Hang F, Gu L, Xu B, Ma D, Zhu G -- Birth Defects Research Part A: Clinical and Molecular Teratology (2013)

BACKGROUND: Previous studies inconsistently suggest that assisted reproduction technology (ART) may increase the risk of birth defects in children. METHOD(S): Live birth infants, conceived by in vitro fertilization fresh embryo transfer (IVF), intracytoplasmic sperm injection fresh embryo transfer (ICSI), or frozen‐thawed embryo transfer (FET) in Reproductive Center of Tongji Hospital (Wuhan, China) between 1997 and 2008, were followed up at birth and after 3 years. Preterm pregnancy, multiple…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:57 GMT</pubDate>
      <dc:creator><![CDATA[Yin L, Hang F, Gu L, Xu B, Ma D, Zhu G]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Assisted reproductive technologies and perinatal morbidity: interrogating the association]]></title>
      <link>https://rrmacademy.org/library/assisted-reproductive-technologies-and-perinatal-morbidity-interrogating-the-ass-xdaicarj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/assisted-reproductive-technologies-and-perinatal-morbidity-interrogating-the-ass-xdaicarj/</guid>
      <description><![CDATA[Barnhart KT -- Fertility and Sterility (2013)

Interrogating the association between assisted reproductive technologies (ART) and perinatal outcome is complicated but very important. This is an introduction to a series of articles that review this potential association with an eye toward etiology of risk, and what aspects of in vitro fertilization (IVF) can be modified to reduce this risk. When an association is not due to chance (i.e., statistically significant), one must also consider how the association may be affected due to bias or…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:57 GMT</pubDate>
      <dc:creator><![CDATA[Barnhart KT]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Congenital malformations associated with assisted reproductive technology: A California statewide analysis]]></title>
      <link>https://rrmacademy.org/library/congenital-malformations-associated-with-assisted-reproductive-technology-a-cali-xwbb0ygs/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/congenital-malformations-associated-with-assisted-reproductive-technology-a-cali-xwbb0ygs/</guid>
      <description><![CDATA[Kelley-Quon LI, Tseng CH, Janzen C, Shew SB -- Journal of Pediatric Surgery (2013)

Background: Management of congenital malformations comprises a large part of pediatric surgical care. Despite increasing utilization of assisted reproductive technology (ART) and fertility-related services (FRS), associations with birth defects are poorly understood.

Methods: Infants born after ART or FRS were identified from the California Linked Birth Cohort Dataset from 2006 to 2007 and compared to propensity matched infants conceived naturally. Factors associated with major congenital…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:55 GMT</pubDate>
      <dc:creator><![CDATA[Kelley-Quon LI, Tseng CH, Janzen C, Shew SB]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Disparities in Obstetrical Outcomes in ART Pregnancies Compared with Natural Conceptions]]></title>
      <link>https://rrmacademy.org/library/disparities-in-obstetrical-outcomes-in-art-pregnancies-compared-with-natural-con-1ycsstba/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/disparities-in-obstetrical-outcomes-in-art-pregnancies-compared-with-natural-con-1ycsstba/</guid>
      <description><![CDATA[Novak C, Spong C, Plowden T -- Seminars in Reproductive Medicine (2013)

Health disparities are observed in all fields of medicine and reproductive health is not immune to this phenomenon. The incidence of women using infertility treatments to conceive is increasing. Women undergoing assisted reproduction appear to be at increased risk of adverse outcomes, and minority women tend to be at even greater risk. This article examines several adverse obstetrical outcomes including preterm birth, congenital malformations, and preeclampsia among women receiving infertility…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:49 GMT</pubDate>
      <dc:creator><![CDATA[Novak C, Spong C, Plowden T]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The impact of assisted reproductive technologies on the genome and epigenome of the newborn]]></title>
      <link>https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-the-genome-and-epigenome-of--b6ooodrb/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-the-genome-and-epigenome-of--b6ooodrb/</guid>
      <description><![CDATA[Kochanski A, Merritt TA, Gadzinowski J, Jopek A -- Journal of Neonatal-Perinatal Medicine (2013)

The question of genetic alterations resulting from assisted reproductive technologies (ART) in humans is examined within the organization of the human genome. Increased rates of birth defects have been reported among children conceived using ART; however, questions remain and controversy exists regarding how "infertility" predisposes to birth defects. ART has been shown to be associated with an increased number of chromosomal alterations especially in the X chromosome. There is increased risk…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:48 GMT</pubDate>
      <dc:creator><![CDATA[Kochanski A, Merritt TA, Gadzinowski J, Jopek A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Impact of ART on pregnancies in California: an analysis of maternity outcomes and insights into the added burden of neonatal intensive care]]></title>
      <link>https://rrmacademy.org/library/impact-of-art-on-pregnancies-in-california-an-analysis-of-maternity-outcomes-and-ute3xhil/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/impact-of-art-on-pregnancies-in-california-an-analysis-of-maternity-outcomes-and-ute3xhil/</guid>
      <description><![CDATA[Merritt TA, Goldstein M, Philips R, Peverini R, Iwakoshi J, Rodriguez A, Oshiro B -- Journal of Perinatology (2014)

Objective: We reviewed the occurrence of prematurity, low birth weight, multiple gestations, frequency of stillbirths and maternity care-associated variables including hospital stay and hospital charges of women conceiving using assisted reproductive technology (ART) or artificial insemination (AI) compared with women with a history of infertility who conceived naturally, and all other naturally conceived pregnancies in California at non-federal hospitals between 2009 and 2011. At a single…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:43 GMT</pubDate>
      <dc:creator><![CDATA[Merritt TA, Goldstein M, Philips R, Peverini R, Iwakoshi J, Rodriguez A, Oshiro B]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Comparison of Congenital Abnormalities of Infants Conceived by Assisted Reproductive Techniques versus Infants with Natural Conception in Tehran]]></title>
      <link>https://rrmacademy.org/library/comparison-of-congenital-abnormalities-of-infants-conceived-by-assisted-reproduc-kkywqn8b/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/comparison-of-congenital-abnormalities-of-infants-conceived-by-assisted-reproduc-kkywqn8b/</guid>
      <description><![CDATA[Farhangniya M, Dortaj Rabori E, Mozafari Kermani R, Haghdoost AA, Bahrampour A, Bagheri P, A L Lancaster P, Ashrafi M, Vosough Taqi Dizaj A, Gourabi H, Shahzadeh Fazeli A -- International journal of fertility & sterility (2013)

BACKGROUND: In many countries, 1 to 3% of newborn infants are conceived by assisted reproductive techniques (ART). Despite the success of ART, there is concern about the risk of congenital malformations among these infants. We report our experience to determine whether use of ART is associated with an increase in major congenital malformations or adverse pregnancy outcomes.

MATERIALS AND METHODS: Historical cohort study of major congenital malformations (MCM) was performed in 978 births from…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:43 GMT</pubDate>
      <dc:creator><![CDATA[Farhangniya M, Dortaj Rabori E, Mozafari Kermani R, Haghdoost AA, Bahrampour A, Bagheri P, A L Lancaster P, Ashrafi M, Vosough Taqi Dizaj A, Gourabi H, Shahzadeh Fazeli A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[[Interconnection between assisted reproductive technologies, pregnancy complications and risk of birth defects]]]></title>
      <link>https://rrmacademy.org/library/interconnection-between-assisted-reproductive-technologies-pregnancy-complicatio-edlqaomx/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/interconnection-between-assisted-reproductive-technologies-pregnancy-complicatio-edlqaomx/</guid>
      <description><![CDATA[Grabar' VV -- Georgian medical news (2014)

The aim of the article was to investigate the relationship between pregnancy complications, infertility and assisted reproductive technologies (ART). The study was conducted on 1331 couples with complicated reproductive history. It is found that miscarriage and other complications of pregnancy depend rather on the etiopathogenesis of infertility than on the technique of ART. The highest frequency of complications of pregnancy was diagnosed in women with endocrine disorders. In case of…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:42 GMT</pubDate>
      <dc:creator><![CDATA[Grabar' VV]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[The impact of assisted reproductive technologies on intra-uterine growth and birth defects in singletons]]></title>
      <link>https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-intrauterine-growth-and-birt-hqtppet5/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-intrauterine-growth-and-birt-hqtppet5/</guid>
      <description><![CDATA[Hansen M, Bower C -- Seminars in Fetal and Neonatal Medicine (2014)

Pooled odds ratios from meta-analyses of infants born following assisted reproductive technologies (ART) compared with non-ART singletons show increases in low birth weight, preterm birth, small for gestational age, and birth defects. Although there have been small reductions in recent data, odds associated with these outcomes are still higher for ART singletons. Both ART procedures and underlying infertility contribute to these increased risks. Outcomes appear better for frozen-thawed compared…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:41 GMT</pubDate>
      <dc:creator><![CDATA[Hansen M, Bower C]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Health and disease in children born after assistive reproductive therapies (ART]]></title>
      <link>https://rrmacademy.org/library/health-and-disease-in-children-born-after-assistive-reproductive-therapies-xxa6xrjs/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/health-and-disease-in-children-born-after-assistive-reproductive-therapies-xxa6xrjs/</guid>
      <description><![CDATA[Hyrapetian M, Loucaides EM, Sutcliffe AG -- Journal of reproductive immunology (2014)

In vitro fertilisation (IVF) and other assisted reproductive therapies (ART) offer hope to subfertile couples worldwide. At least 5 million ART children have been born to date. Their health is an issue that is increasingly relevant: first, to those children and young adults themselves; second, to couples considering fertility treatment; and third, to the general population as ART has progressed from experimental treatment to routine practice. Many concerns about the potential risks to these…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:40 GMT</pubDate>
      <dc:creator><![CDATA[Hyrapetian M, Loucaides EM, Sutcliffe AG]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Pregnancy-related complications and adverse pregnancy outcomes in multiple pregnancies resulting from assisted reproductive technology: a meta-analysis of cohort studies]]></title>
      <link>https://rrmacademy.org/library/pregnancyrelated-complications-and-adverse-pregnancy-outcomes-in-multiple-pregna-owkpffcx/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/pregnancyrelated-complications-and-adverse-pregnancy-outcomes-in-multiple-pregna-owkpffcx/</guid>
      <description><![CDATA[Qin J, Wang H, Sheng X, Liang D, Tan H, Xia J -- Fertility and Sterility (2015)

Objective: To provide an up-to-date comparison of pregnancy-related complications and adverse pregnancy outcomes of multiple pregnancies generated with assisted reproductive technology (ART) vs. spontaneous conception.

Design: Meta-analysis.

Setting: University-affiliated teaching hospital.Patient(s)Multiple pregnancies conceived by ART or naturally.Intervention(s)Searches through October 2014 were conducted on PubMed, Google Scholar, Cochrane Libraries, China Biology Medicine disc, Chinese…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:39 GMT</pubDate>
      <dc:creator><![CDATA[Qin J, Wang H, Sheng X, Liang D, Tan H, Xia J]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Surveillance of congenital malformations in infants conceived through assisted reproductive technology or other fertility treatments]]></title>
      <link>https://rrmacademy.org/library/surveillance-of-congenital-malformations-in-infants-conceived-through-assisted-r-7varj7eo/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/surveillance-of-congenital-malformations-in-infants-conceived-through-assisted-r-7varj7eo/</guid>
      <description><![CDATA[Heisey AS, Bell EM, Herdt‐Losavio ML, Druschel C -- Birth Defects Research Part A: Clinical and Molecular Teratology (2015)

Background: As assisted reproductive technology (ART) becomes more common, it is important to understand the associated risks. The objective of this study was to determine if congenital malformations are associated with ART or other fertility treatments in New York.

Methods: In a retrospective cohort study of all live births in upstate New York from 1997 to 2005, exposure was defined using ART or other fertility treatments as noted on birth certificates. Outcomes were assessed from the New…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:39 GMT</pubDate>
      <dc:creator><![CDATA[Heisey AS, Bell EM, Herdt‐Losavio ML, Druschel C]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[A rare presentation of aplasia cutis congenita after feto-reduction in a trichorionic-triamniotic pregnancy]]></title>
      <link>https://rrmacademy.org/library/a-rare-presentation-of-aplasia-cutis-congenita-after-fetoreduction-in-a-trichori-tmhqpcsy/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/a-rare-presentation-of-aplasia-cutis-congenita-after-fetoreduction-in-a-trichori-tmhqpcsy/</guid>
      <description><![CDATA[Vettori D, Jairath P -- Journal of Neonatal-Perinatal Medicine (2015)

Aplasia cutis congenita (ACC) is rare skin disorder of newborns that has been linked to both assisted reproductive technology (ART) and feto-reduction procedures. ACC is characterized by well-demarcated lesions that are devoid of all skin layers. Group-V ACC presents with a distinctive and symmetrical distribution pattern. It is thought to result from an insult to the fetus after concomitant twin demise and is almost exclusively reported in monochorionic gestations.A 41-year-old female with an…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:38 GMT</pubDate>
      <dc:creator><![CDATA[Vettori D, Jairath P]]></dc:creator>
      <category>Pregnancy</category>
    </item>
    <item>
      <title><![CDATA[The impact of assisted reproductive technologies on genomic imprinting and imprinting disorders]]></title>
      <link>https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-genomic-imprinting-and-impri-5nfbj40v/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/the-impact-of-assisted-reproductive-technologies-on-genomic-imprinting-and-impri-5nfbj40v/</guid>
      <description><![CDATA[Uyar A, Seli E -- Current Opinion in Obstetrics &amp; Gynecology (2014)

Purpose of reviewGenomic imprinting refers to preferential allele-specific gene expression. DNA methylation-based molecular mechanisms regulate establishment and maintenance of parental imprints during early embryo development and gametogenesis. Because of the coincident timing, a potential association between assisted reproductive technology (ART) procedures and imprinting defects has been investigated in various studies. In this review, we provide an overview of genomic imprinting and present…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:37 GMT</pubDate>
      <dc:creator><![CDATA[Uyar A, Seli E]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Long-term follow-up of children conceived through assisted reproductive technology]]></title>
      <link>https://rrmacademy.org/library/longterm-followup-of-children-conceived-through-assisted-reproductive-technology-bras3ckr/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/longterm-followup-of-children-conceived-through-assisted-reproductive-technology-bras3ckr/</guid>
      <description><![CDATA[Lu Yh, Wang N, Jin F -- Journal of Zhejiang University SCIENCE B (2013)

The binding of Ca2+ to monolayers and bilayers of phosphatidylserine has been investigated as a function of pH, ionic strength (NaCl concentration) and Ca2+ concentration using surface and colloid chemical techniques. The molar ratio of lipid to bound calcium decreases to 2 as the Ca2+ concentration is increased to about 0.1 mM. At [Ca2+] greater than 0.1 mM a 1:1 complex is formed. The apparent binding constant Ka ranges from about approximately 10(6) - 10(4) l/mol depending on the Ca2+…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:37 GMT</pubDate>
      <dc:creator><![CDATA[Lu Yh, Wang N, Jin F]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Child with Beckwith-Wiedemann syndrome born after assisted reproductive techniques to an human immunodeficiency virus serodiscordant couple]]></title>
      <link>https://rrmacademy.org/library/child-with-beckwithwiedemann-syndrome-born-after-assisted-reproductive-technique-ev8bzhj1/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/child-with-beckwithwiedemann-syndrome-born-after-assisted-reproductive-technique-ev8bzhj1/</guid>
      <description><![CDATA[Kuentz P, Bailly A, Faure AC, Blagosklonov O, Amiot C, Bresson JL, Roux C -- Fertility and Sterility (2011)

Objective: To report a child with Beckwith-Wiedemann syndrome (BWS) born after assisted reproductive technology (ART) to an HIV serodiscordant couple.

Design: Case report.

Setting: Academic medical center.Patient(s)A child with BWS born after ART to an HIV serodiscordant couple.Intervention(s)Assisted reproductive techniques.Main outcome measure(s)ART and HIV.Result(s)Since 2003, it has been suggested that there is an association between ART and BWS, which is a congenital overgrowth syndrome…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:36 GMT</pubDate>
      <dc:creator><![CDATA[Kuentz P, Bailly A, Faure AC, Blagosklonov O, Amiot C, Bresson JL, Roux C]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Is it the patient or the IVF? Beckwith-Wiedemann syndrome in both spontaneous and assisted reproductive conceptions]]></title>
      <link>https://rrmacademy.org/library/is-it-the-patient-or-the-ivf-beckwithwiedemann-syndrome-in-both-spontaneous-and--2ur2vwcw/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/is-it-the-patient-or-the-ivf-beckwithwiedemann-syndrome-in-both-spontaneous-and--2ur2vwcw/</guid>
      <description><![CDATA[Strawn EY, Bick D, Swanson A -- Fertility and Sterility (2010)

Objective: To describe two children diagnosed with Beckwith-Wiedemann Syndrome (BWS) arising from a spontaneous conception and an assisted reproductive technology (ART) cycle from one patient with a long-standing history of subfertility.

Design: Case report.

Setting: Academic medical center.Patient(s)Two children with the morphologic features of BWS as a result of a spontaneous conception and an ART cycle from the same patient.Intervention(s)Assisted reproductive technology.Main outcome…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:35 GMT</pubDate>
      <dc:creator><![CDATA[Strawn EY, Bick D, Swanson A]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[[Retrospective studies of pregnancies after assisted medical reproduction from 2001-2009 and Central Hospital in Luxembourg (part 2)]]]></title>
      <link>https://rrmacademy.org/library/retrospective-studies-of-pregnancies-after-assisted-medical-reproduction-from-20-57dsvjsx/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/retrospective-studies-of-pregnancies-after-assisted-medical-reproduction-from-20-57dsvjsx/</guid>
      <description><![CDATA[Arendt J, Schilling C, Peiffer M, Ginter S, Nahanb AF, Lemosb C, Duboisb M, Thononb F, Jouanb C, Gaspardb O, Larcher ME, Gomez V, Pereira S, Geimer M -- Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg (2010)

The first chapter analyses the ART methods of the Centre Hospitalier of Luxembourg, in the department of reproductive medicine between 2001 and 2009. The second chapter examines the techniques individually, their influence on pregnancy outcomes, the complications on offsprings and their health. The results coincide with literature in that risks are acceptable as long as good medical and biological conditions are maintained. Multiple pregnancies remain the most frequent complication,…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:35 GMT</pubDate>
      <dc:creator><![CDATA[Arendt J, Schilling C, Peiffer M, Ginter S, Nahanb AF, Lemosb C, Duboisb M, Thononb F, Jouanb C, Gaspardb O, Larcher ME, Gomez V, Pereira S, Geimer M]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Managing the complications associated with assisted reproductive technologies]]></title>
      <link>https://rrmacademy.org/library/managing-the-complications-associated-with-assisted-reproductive-technologies-xgjswrhj/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/managing-the-complications-associated-with-assisted-reproductive-technologies-xgjswrhj/</guid>
      <description><![CDATA[Patchava S, Gelbaya TA, Nardo LG -- Minerva ginecologica (2009)

Delaying conception has increased the demand on assisted reproduction. Currently, more than 1% of children are conceived through assisted reproductive technologies (ART) worldwide and this number is likely to continue increasing. Like any other medical intervention ART is associated with both short-term and long-term complications. The major short-term complications include ovarian hyperstimulation syndrome (OHSS) and multiple pregnancies. OHSS is difficult to predict, but meticulous preventive…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:34 GMT</pubDate>
      <dc:creator><![CDATA[Patchava S, Gelbaya TA, Nardo LG]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Assisted reproductive technology and major structural birth defects in the United States]]></title>
      <link>https://rrmacademy.org/library/assisted-reproductive-technology-and-major-structural-birth-defects-in-the-unite-igndzi3u/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/assisted-reproductive-technology-and-major-structural-birth-defects-in-the-unite-igndzi3u/</guid>
      <description><![CDATA[Reefhuis J, Honein M, Schieve L, Correa A, Hobbs C, Rasmussen S,  -- Human Reproduction (2009)

Background: With >1% of US births occurring following use of assisted reproductive technology (ART), it is critical to examine whether ART is associated with birth defects.

Methods: We analyzed data from the National Birth Defects Prevention Study, a population-based, multicenter, case-control study of birth defects. We included mothers of fetuses or live-born infants with a major birth defect (case infants) and mothers who had live-born infants who did not have a major birth defect (control…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:33 GMT</pubDate>
      <dc:creator><![CDATA[Reefhuis J, Honein M, Schieve L, Correa A, Hobbs C, Rasmussen S, ]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Assisted reproductive technology may increase clinical mutation detection in male offspring]]></title>
      <link>https://rrmacademy.org/library/assisted-reproductive-technology-may-increase-clinical-mutation-detection-in-mal-pekwjoek/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/assisted-reproductive-technology-may-increase-clinical-mutation-detection-in-mal-pekwjoek/</guid>
      <description><![CDATA[Feng C, Wang LQ, Dong MY, Huang HF -- Fertility and Sterility (2008)

Objective: To investigate the risks of chromosome mutation after ART for couples with comparable genetic backgrounds.

Design: Prospective clinical observational study.

Setting: In vitro fertilization center at a tertiary-care, university-affiliated teaching hospital.Patient(s)Ninety-seven male children whose fathers have normal spermatogenesis were recruited, including 19 babies conceived through IVF, 18 babies conceived through intracytoplasmic sperm injection (ICSI), and 60 naturally…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:33 GMT</pubDate>
      <dc:creator><![CDATA[Feng C, Wang LQ, Dong MY, Huang HF]]></dc:creator>
      <category>Andrology/Male Factor</category>
    </item>
    <item>
      <title><![CDATA[Obstetric Outcomes and Congenital Abnormalities After In Vitro Maturation, In Vitro Fertilization, and Intracytoplasmic Sperm Injection]]></title>
      <link>https://rrmacademy.org/library/obstetric-outcomes-and-congenital-abnormalities-after-in-vitro-maturation-in-vit-ds2zzrjh/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/obstetric-outcomes-and-congenital-abnormalities-after-in-vitro-maturation-in-vit-ds2zzrjh/</guid>
      <description><![CDATA[Patrizio P -- Yearbook of Neonatal and Perinatal Medicine (2008)]]></description>
      <pubDate>Sat, 02 May 2026 05:24:32 GMT</pubDate>
      <dc:creator><![CDATA[Patrizio P]]></dc:creator>
      <category>Infertility</category>
    </item>
    <item>
      <title><![CDATA[Silver-Russell syndrome in a girl born after in vitro fertilization: partial hypermethylation at the differentially methylated region of PEG1/MEST]]></title>
      <link>https://rrmacademy.org/library/silverrussell-syndrome-in-a-girl-born-after-in-vitro-fertilization-partial-hyper-7a1j9c0z/</link>
      <guid isPermaLink="true">https://rrmacademy.org/library/silverrussell-syndrome-in-a-girl-born-after-in-vitro-fertilization-partial-hyper-7a1j9c0z/</guid>
      <description><![CDATA[Kagami M, Nagai T, Fukami M, Yamazawa K, Ogata T -- Journal of Assisted Reproduction and Genetics (2007)

A group of patients has been identified with cutaneous necrotizing venulitis (vasculitis). These patients, some with concomitant connective tissue disorders, have skin lesions that separate them from the arteritis commonly described as rheumatoid vasculitis. HLA typing has been performed on 31 of these unrelated patients with cutaneous necrotizing venulitis, including 19 with associated chronic disorders. The antigen pair A11, BW35 was found in 5 of these 19 patients and in 11 of 346 controls.…]]></description>
      <pubDate>Sat, 02 May 2026 05:24:31 GMT</pubDate>
      <dc:creator><![CDATA[Kagami M, Nagai T, Fukami M, Yamazawa K, Ogata T]]></dc:creator>
      <category>Infertility</category>
    </item>
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