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Nature, 2026

Lipid metabolism drives dietary effects on T cell ferroptosis and immunity

Wang N, Chen Z, Yao Y, Sun C, Wei W, Sun L, Zhang H, Li F, Butcher D, Sun SR, Gong J, Jiang YC, Qi Y, Huang J, Nettelfield S, Liu R, Zheng X, Li C, Fu Y, Geng H, Zhao L, Sun H, Yang Y, Ge Y, Pazhouhandeh M, Barlow CK, Jeppe KJ, Yunis J, Zhu C, Wei Y, Liang X, Bridle K, Frazer DM, Tey SK, Li Y, Yang Z, Shu M, Liu Z, Crawford D, Yu D

DOI10.1038/s41586-026-10193-4 PMID41781622
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Topics

General OB/GYN > Nutrition > Lipid Metabolism and ImmunityResearch Methodology > Basic Science > Immunometabolism
lipid metabolism T cell ferroptosis dietary effects, dietary fat T cell immunity ferroptosis, lipid metabolism adaptive immunity T cell function, ferroptosis immune regulation diet, T cell ferroptosis lipid peroxidation dietary intervention, nutritional immunology T cell lipid metabolism, dietary effects on T cell function ferroptosis pathway, iron dependent cell death T cells lipid metabolism, Wang Sun Nature ferroptosis immunity diet, metabolic regulation T cell antitumor immunity
PMID 41781622 41781622 DOI 10.1038/s41586-026-10193-4 10.1038/s41586-026-10193-4

Cite this article

Wang, N., Chen, Z., Yao, Y., Sun, C., Wei, W., Sun, L., Zhang, H., Li, F., Butcher, D., Sun, S. R., Gong, J., Jiang, Y. C., Qi, Y., Huang, J., Nettelfield, S., Liu, R., Zheng, X., Li, C., Fu, Y., . . . Yu, D. (2026). Lipid metabolism drives dietary effects on T cell ferroptosis and immunity. *Nature*. https://doi.org/10.1038/s41586-026-10193-4

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