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Abstract

Objective

To evaluate the effects of coital lubricants and oils on sperm motility.

Design

Comparative prospective in vitro study.

Setting

University Andrology laboratory.

PATIENT(S): Twenty-two normozoospermic donors.

INTERVENTION(S): Semen samples were incubated in modified human tubal fluid (mHTF) control and in 10% Pre-Seed, Astroglide, and KY products (Sensitive, Warming, and Tingling) and baby, canola, sesame, and mustard oils. Total and progressive sperm motility was evaluated before and at 5, 30, and 60 minutes of incubation.

MAIN OUTCOME MEASURE(S): Sperm motility.

RESULT(S): Control samples exhibited no significant decrease in sperm motility. Pre-Seed showed a slight (∼4%) but significant drop in progressive motility after 30 minutes. Total and progressive sperm motility significantly declined under Astroglide, KY products (Sensitive, Warming, and Tingling) and sesame oil incubation. Canola oil significantly decreased total motility after 30 minutes and progressive motility after 5 minutes of incubation. Similarly, baby oil decreased total motility after 60 minutes and progressive motility after 5 minutes. After initial decline, total and progressive sperm motility under Pre-Seed and canola and baby oils remained high. Exposure to mustard oil caused persistent hyperactivation of sperm in each sample with no decrease in motility.

CONCLUSION(S): Sesame oil and synthetic coital lubricants impaired sperm motility and may hamper fertility. Pre-Seed and canola, mustard, and baby oils showed no deleterious effect and may be considered sperm-friendly coital lubricants. Mustard oil exposure resulted in hyperactivation of sperm and needs to be studied further.

Topics

Pregnancy > Conception Optimization > Lubricant Effects on SpermAndrology > Sperm Function > Motility AssessmentInfertility > Lifestyle Factors > Lubricant Selection
coital lubricant sperm motility in vitro effects, Pre-Seed Astroglide KY sperm friendly lubricant comparison, natural oils sperm motility canola baby mustard oil, lubricant effect on fertility sperm progressive motility, sperm-safe lubricant trying to conceive, sesame oil sperm impairment in vitro study, mustard oil sperm hyperactivation motility, vaginal lubricant fertility impact normozoospermic donors, synthetic lubricant versus natural oil sperm function, coital lubricant selection couples attempting pregnancy
PMID 24462060 24462060 DOI 10.1016/j.fertnstert.2013.12.024 10.1016/j.fertnstert.2013.12.024

Cite this article

Sandhu, R. S., Wong, T. H., Kling, C. A., & Chohan, K. R. (2014). In vitro effects of coital lubricants and synthetic and natural oils on sperm motility. *Fertility and sterility*, *101*(4), 941-944. https://doi.org/10.1016/j.fertnstert.2013.12.024

Keywords

Adult, Cells, Cultured, Glycerol/pharmacology, Humans, In Vitro Techniques, Lubricants/pharmacology, Male, Mineral Oil/pharmacology, Plant Oils/pharmacology, Sperm Motility/drug Effects/physiology, Vaginal Creams, Foams, and Jellies/pharmacology, Astroglide, Lubricants, Plant Oils, Vaginal Creams, Foams, and Jellies, Mineral Oil, Glycerol, Sperm, Coital, Lubricants, Motility, Oils

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