International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics, 20(1), 13-17, 1982
Evaluation of the use of Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy
This study evaluates the effect of treatment with Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy, and the final outcome of pregnancy and fetal status. One hundred and fifty patients received intramuscular injection of Proluton-Depot from 6 weeks to 8 weeks to 16 weeks to 18 weeks gestation. The outcome of this treated group was compared with a similar number of 150 patients with similar problems, but the second group received no hormonal treatment. There was no evidence to suggest that Proluton-Depot had any adverse effect on the infant or the final outcome of pregnancy.
hydroxyprogesterone hexanoate early pregnancy outcome, Proluton Depot progesterone supplementation first trimester, intramuscular progesterone early pregnancy fetal safety, hydroxyprogesterone caproate threatened pregnancy treatment, Varma Morsman Proluton Depot pregnancy evaluation, progesterone support early pregnancy threatened abortion, hormonal treatment first trimester pregnancy outcome, progestogen supplementation fetal safety assessment, case-controlled progesterone treatment early gestation, injectable progesterone pregnancy maintenance fetal outcome
PMID 6126401 6126401 DOI 10.1016/0020-7292(82)90039-x 10.1016/0020-7292(82)90039-x
Cite this article
Varma, T. R., & Morsman, J. (1982). Evaluation of the use of Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy. *International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics*, *20*(1), 13-17. https://doi.org/10.1016/0020-7292(82)90039-x
Varma TR, Morsman J. Evaluation of the use of Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy. Int J Gynaecol Obstet. 1982;20(1):13-17. doi:10.1016/0020-7292(82)90039-x
Varma, T. R., and J. Morsman. "Evaluation of the use of Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy." *International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics*, vol. 20, no. 1, 1982, pp. 13-17.
Keywords
17 alpha-Hydroxyprogesterone Caproate, Abnormalities, Drug-Induced/etiology, Abortion, Spontaneous/drug Therapy, Adult, Corpus Luteum Maintenance/drug Effects, Female, Humans, Hydroxyprogesterones/adverse Effects/therapeutic Use, Infant, Newborn, Infertility, Female/drug Therapy, Outcome and Process Assessment, Health Care, Pregnancy, Prenatal Exposure Delayed Effects, Hydroxyprogesterones, 17 alpha-Hydroxyprogesterone Caproate
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