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Abstract

Summary

Studies on pituitary and ovarian function as assessed by the urinary output of total gonadotrophic activity, the three classical oestrogens, pregnanediol and, in some cases, testosterone and epitestosterone, were conducted in eight patients suffering from premenstrual tension. Major abnormalities in endocrine function were not a feature of the condition. Ovulation, as judged by pregnanediol assays, was absent in seven out of the fifteen cycles investigated. Contrary to traditional belief, the symptoms of premenstrual tension could exist in the presence of cycles with anovulatory hormonal patterns.

Topics

Menstrual Cycle > Premenstrual Disorders > Hormonal ProfilesReproductive Endocrinology > Ovarian Function > Anovulation and PMSMenstrual Cycle > Luteal Phase > Premenstrual Syndrome Etiology
premenstrual tension endocrine profiles hormonal, premenstrual syndrome anovulatory cycles hormones, PMS estrogen progesterone pregnanediol gonadotropin levels, premenstrual tension anovulation symptom persistence, Adamopoulos Loraine premenstrual tension endocrine 1972, premenstrual symptoms without ovulation hormonal patterns, urinary estrogen pregnanediol testosterone premenstrual syndrome, pituitary ovarian function premenstrual tension, anovulatory cycles premenstrual symptoms endocrine, premenstrual disorder hormonal etiology investigation
PMID 4677133 4677133 DOI 10.1111/j.1365-2265.1972.tb00400.x 10.1111/j.1365-2265.1972.tb00400.x

Cite this article

Adamopoulos, D. A., Loraine, J. A., Lunn, S. F., Coppen, A. J., & Daly, R. J. (1972). Endocrine profiles in premenstrual tension. *Clinical endocrinology*, *1*(3), 283-292. https://doi.org/10.1111/j.1365-2265.1972.tb00400.x

Keywords

Adult, Estradiol/urine, Estriol/urine, Estrogens/urine, Estrone/urine, Female, Gonadotropins/urine, Humans, Pregnanediol/urine, Premenstrual Syndrome/urine, Testosterone/urine, Estrogens, Gonadotropins, Estrone, Testosterone, Estradiol, Estriol, Pregnanediol

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