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Abstract

In a consecutive series of 167 patients reaching the stage of embryo transfer after in vitro fertilization and embryo transfer, 19 clinical pregnancies ensued. The serum progesterone (P) levels were significantly greater on the first and second (P less than 0.01) and third (P less than 0.05) postaspiration days for those who conceived. Higher circulating levels of P were achieved on days 1, 2, and 3 (P less than 0.05) by the daily injection of P, 50 mg in oil, given for 5 consecutive days, beginning immediately after follicle aspiration. Both pregnancy and nonpregnancy cycles demonstrated high circulating P levels, but the study implies that relatively higher levels are required for conception, and such levels can be achieved by the use of intramuscular P.

Topics

Infertility > IVF > Luteal Phase SupportReproductive Endocrinology > Progesterone > Luteal Phase LevelsDiagnostics > Hormonal Assessment > Progesterone Monitoring
early luteal progesterone levels pregnancy prediction IVF, serum progesterone concentration embryo transfer pregnancy outcome, Yovich luteal progesterone IVF pregnancy cycles, progesterone supplementation intramuscular oil after follicle aspiration, luteal phase progesterone support in vitro fertilization, post-aspiration progesterone levels conception prediction, early luteal phase progesterone higher pregnancy cycles, progesterone 50mg intramuscular IVF luteal support, serum progesterone day 1 2 3 post-aspiration pregnancy, luteal insufficiency IVF progesterone supplementation outcomes
PMID 3926544 3926544 DOI 10.1016/s0015-0282(16)48733-9 10.1016/s0015-0282(16)48733-9

Cite this article

Yovich, J. L., McColm, S. C., Yovich, J. M., & Matson, P. L. (1985). Early luteal serum progesterone concentrations are higher in pregnancy cycles. *Fertility and sterility*, *44*(2), 185-189. https://doi.org/10.1016/s0015-0282(16)48733-9

Keywords

Clinical Trials As Topic, Clomiphene/pharmacology, Embryo Transfer, Female, Fertilization in Vitro, Humans, Luteal Phase, Menotropins/pharmacology, Ovulation Induction, Pregnancy, Progesterone/blood/pharmacology, Clomiphene, Progesterone, Menotropins

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