American Journal of Reproductive Immunology (New York, N.Y. : 1989), 75(1), 13-22, 2015

Chronic Endometritis: Potential Cause of Infertility and Obstetric and Neonatal Complications

Tomomoto Ishikawa , Kotaro Kitaya , Hidehiko Matsubayashi

Author affiliations (3)
  • Osaka Nishi Clinic ROR
  • Kansai Medical University ROR
  • Kyoto Prefectural University of Medicine ROR
DOI10.1111/aji.12438 PMID26478517
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Abstract

Chronic endometritis (CE) is a local inflammatory disease characterized by unusual plasmacyte infiltration in the endometrial stromal areas. CE has been neglected in gynecologic practice, as it is a less symptomatic benign disease that requires demanding and time-consuming histopathologic examinations for the definite diagnosis. Recent studies, however, suggest the association of CE with infertility and obstetric and neonatal complications. In this review article, we aimed to update the knowledge on epidemiology, etiology, and pathogenesis of CE as well as discuss its clinical management from diagnosis to treatment.

Topics

chronic endometritis infertility review, chronic endometritis obstetric neonatal complications, plasmacyte infiltration endometrial stroma diagnosis, chronic endometritis epidemiology etiology pathogenesis, endometrial inflammation recurrent implantation failure, chronic endometritis histopathologic diagnosis treatment, Kitaya chronic endometritis plasma cells, uterine infection infertility management, endometritis antibiotic treatment fertility outcomes, subclinical endometritis reproductive failure review
PMID 26478517 26478517 DOI 10.1111/aji.12438 10.1111/aji.12438

Cite this article

Kitaya, K., Matsubayashi, H., Yamaguchi, K., Nishiyama, R., Takaya, Y., Ishikawa, T., Yasuo, T., & Yamada, H. (2016). Chronic Endometritis: Potential Cause of Infertility and Obstetric and Neonatal Complications. *American journal of reproductive immunology (New York, N.Y. : 1989)*, *75*(1), 13-22. https://doi.org/10.1111/aji.12438

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